A comparison of death rates associated with COVID-19 versus influenza during Fall-Winter 2022-23

A comparability of dying charges related to COVID-19 versus influenza throughout Fall-Winter 2022-23

In a latest research printed in JAMA Journal, researchers in contrast the dying charges related to coronavirus illness 2019 (COVID-19) with that of seasonal influenza through the 2022-2023 fall-winter season.

Research: Danger of dying in sufferers hospitalized for COVID-19 vs seasonal influenza in autumn-winter 2022-2023. Picture Credit score: CROCOTHERY/Shutterstock.com


In the course of the early levels of the COVID-19 pandemic, dying charges related to extreme acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections had been considered 5 instances greater than these from seasonal influenza infections.

Nevertheless, the fast improvement of COVID-19 vaccines and varied therapies, together with antivirals and monoclonal antibodies, have considerably lowered the variety of deaths from SARS-CoV-2 infections.

As well as, scientific care amenities and population-level immunity in opposition to SARS-CoV-2 have additionally improved, which has lowered the variety of deaths on account of COVID-19.

These adjustments can also have affected the dying charges related to the seasonal influenza virus.

Concerning the studio

The researchers used the US Division of Veterans Affairs digital well being databases to enroll research contributors.

Contributors had a minimum of a report of hospitalization between October 2020 and January 2023, two days earlier than and ten days after a constructive take a look at for influenza or SARS-CoV-2 together with a analysis of influenza or COVID-19 on the time of admission. People with each infections had been excluded.

Contributors had been adopted up for 30 days after hospitalization, till the primary dying occasion or till March 2, 2023. Absolute standardized variations had been used to research baseline traits for all contributors.

Inverse chance weighted Cox survival fashions had been used to check the mortality danger between sufferers hospitalized with influenza and COVID-19.

Propensity scores had been calculated bearing in mind covariates. Absolute danger was additionally calculated primarily based on the distinction in 30-day mortality charges between COVID-10 and influenza as a share of extra deaths.

Moreover, danger analyzes had been carried out by subgroups primarily based on age, COVID-19 vaccination standing, severity of SARS-CoV-2 an infection, and outpatient therapy with COVID-19 antivirals previous to hospitalization.


The outcomes indicated that the dying price related to COVID-19 among the many veteran inhabitants through the 2022-2023 fall-winter season continued to be greater than that of seasonal influenza infections.

In the course of the research interval, there have been 8,996 hospital admissions on account of COVID-19, amongst which there have been 538 deaths, whereas there have been 76 deaths amongst 2,403 sufferers hospitalized for seasonal influenza.

At 30 days, the mortality charges from SARS-CoV-2 an infection and seasonal influenza had been 5.97% and three.75%, respectively, with an extra mortality price of two.23%.

Subgroup evaluation revealed that COVID-19 vaccination was linked to a lower within the dying price, however different elements within the subgroup evaluation, corresponding to age and outpatient antiviral therapy, didn’t affect charges of mortality.

Though dying charges related to COVID-19 proceed to be greater than dying charges from seasonal influenza, it must be famous that dying charges from extreme SARS-CoV-2 infections requiring hospitalization have decreased markedly since 2020 (when mortality charges ranged from 17% to 21%). Demise charges from seasonal flu have remained comparatively secure since 2020 (3.8% versus 3.7% in 2023).

Researchers imagine that the lower within the dying price from COVID-19 could possibly be on account of a number of elements. These embrace the emergence of recent SARS-CoV-2 variants with decrease virulence, elevated immunity from a number of doses of SARS-CoV-2 vaccines and infections, and a big enchancment in scientific care.

The distinction in mortality charges between unvaccinated people and vaccinated or boosted people highlights the significance of COVID-19 vaccines in decreasing the severity and mortality related to COVID-19.

One limitation of the research is that the research inhabitants was composed predominantly of older male veterans, making it tough to generalize the findings to the bigger inhabitants.


General, the outcomes indicated that COVID-19 dying charges had declined considerably because the begin of the pandemic. Nevertheless, deaths stay greater than these from seasonal flu.

Nevertheless, major and booster vaccines have considerably lowered COVID-19 mortality charges, highlighting the protecting results of vaccines.

Written by

Physician Chinta Sidharthan

Chinta Sidharthan is a author primarily based in Bangalore, India. His educational background is in evolutionary biology and genetics and he has intensive expertise in scientific analysis, instructing, scientific writing and herpetology. Chinta holds a PhD. in evolutionary biology from the Indian Institute of Science and is captivated with science training, writing, animals, wildlife and conservation. For his doctoral analysis, he explored the origins and diversification of blind snakes in India, as a part of which he did intensive fieldwork within the jungles of southern India. He has been awarded the Canadian Governor Common’s Bronze Medal and the Bangalore College Gold Medal for Tutorial Excellence and has had his analysis printed in impactful journals.


Please use one of many following codecs to quote this text in your essay, article or report:

  • APA extension

    Sidharthan, Chinta. (2023, April 10). A comparability of dying charges related to COVID-19 versus influenza throughout Fall-Winter 2022-23. Information-doctor. Retrieved April 10, 2023 from https://www.news-medical.web/information/20230410/A-comparison-of-death-rates-associated-with-COVID-19-versus-influenza-during-fall-winter – 2022-23.aspx.

  • MLA extension

    Sidharthan, Chinta. “A Comparability of Demise Charges Related to COVID-19 Versus Influenza Throughout Fall-Winter 2022-23.” Information-doctor. April 10, 2023. .

  • Chicago

    Sidharthan, Chinta. “A Comparability of Demise Charges Related to COVID-19 Versus Influenza Throughout Fall-Winter 2022-23.” Information-doctor. https://www.news-medical.web/information/20230410/A-comparison-of-death-rates-associated-with-COVID-19-versus-influenza-during-fall-winter-2022-23.aspx. (accessed April 10, 2023).

  • Harvard

    Sidharthan, Chinta. 2023. A comparability of dying charges related to COVID-19 versus influenza throughout Fall-Winter 2022-23. Information-Medical, considered April 10, 2023, https://www.news-medical.web/information/20230410/A-comparison-of-death-rates-associated-with-COVID-19-versus-influenza-during- fall -winter-2022-23.aspx.

Author: ZeroToHero

Leave a Reply

Your email address will not be published. Required fields are marked *